SARS-Cov-2: From Indian to Omicron New Variants: Descriptive Minireview
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Abstract
A new type of coronavirus called BA.5 is causing a stir because it is more evolved than other Omicron variants. However, BA.5 strategically circumvents the accumulated defenses against previous versions of the virus. All this means that cases of reinfection are on the rise, including among newly vaccinated and infected people.
The most common symptoms of the original Omicron strain include runny nose, sneezing and sore throat. Headache, muscle aches, coughing, sneezing, high temperature, pressure in the ears and face, and loss of taste and smell, especially in vaccinated persons. Diarrhea and anorexia are likely linked to Covid-19, but the two lists of symptoms are nearly identical. , now seems to be lurking everywhere and infecting everyone, whether they already have a vaccine, have booster shots, or have a recent bout of COVID-19. “If you have BA.1, you are not adequately protected against BA.4/5”.The purpose of this short descriptive review in General
Is to To shed light on the occurrence and implications of various mutations in SARS-CoV-2 to date.
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References
I. Lu R, Zhao X, Li J, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020; 395(10224): 565- 574.
II. 54Omicron variant: what you need to know. Updated December 10, 2021. https://www.cdc.gov/coronavirus/2019-ncov/variants/omicron-variant.html
III. World Health Organization. Novel Coronavirus (2019-nCoV) Available at
https://www.who.int/emergencies/diseases/novel-coronavirus-2019. Accessed February 7, 2020.
IV. Singh J, Rahman SA, Ehtesham NZ, Hira S, Hasnain SE. SARS-CoV-2 variants of concern are emerging in India. Nat Med. 2021; 27(7): 1131- 1133.
V. Huang C, Wang Y, Li X, et al. (2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet, 395: 497-506.
VI. Wu YC, Chen CS, Chan YJ. The outbreak of COVID-19: An overview. J Chin Med Assoc. 2020;83(3):217-220. doi:10.1097/JCMA.0000000000000270
VII. Nguyen, T.T., Pathirana, P.N., Nguyen, T. et al. Genomic mutations and changes in protein secondary structure and solvent accessibility of SARS-CoV-2 (COVID-19 virus). Sci Rep 11, 3487 (2021). https://doi.org/10.1038/s41598-021-83105-3
VIII. Chen AT, Altschuler K, Zhan SH, Chan YA, Deverman BE. COVID-19 CG: Tracking SARS-CoV-2 mutations by locations and dates of interest. Preprint. bioRxiv. 2020; 2020.09.23.310565. Published 2020 Sep 28.
doi:10.1101/2020.09.23.310565
IX. Covid-19: WHO warns against “vaccine nationalism” or face further virus mutations BMJ 2021; 372 doi: https://doi.org/10.1136/bmj.n292
X. A.A.Dawood .Mutated COVID-19 may foretell a great risk for mankind I n the future. New Microbes and New Infections Volume 35, May 2020, 100673
XI. H.A. Rothan, S.N. Byrareddy The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak .J Autoimm (2020), 10.1016/j.jaut.2020.102433
XII. Robinson J, Banerjee I, Leclézio A, Sathian B. COVID-19 and mutations a threat level assessment. Nepal J Epidemiol. 2021; 11(1):983-987. Published 2021 Mar 31. doi:10.3126/nje.v11i1.35659
XIII. Mahase E. Covid-19: What have we learnt about the new variant in the UK? BMJ. 2020. December 23; 371:m4944. 10.1136/bmj.m4944 PMid:
XIV. Wang P, Nair MS, Liu L, et al. . Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7. Nature. 2021. March 8. 10.1038/s41586-021-03398-2 PMid: .
XV. Almubaid Z, Al-Mubaid H. Analysis and comparison of genetic variants and mutations of the novel coronavirus SARS-CoV-2. Gene Rep. 2021. June;23:101064. 10.1016/j.genrep.2021.101064 PMid: PMCid:
XVI. Tang JW, Toovey OT, Harvey KN, Hui DD. Introduction of the South African SARS-CoV-2 variant 501Y. V2 into the UK. The Journal of infection. 2021. January 17.
1016/j.jinf.2021.01.007 PMid: PMCid