Prevalence of Uropathogen and Antibiotic Susceptibility Pattern in Urinary Tract Infection: A Reterospective Observational Cohort Study

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Dr.Roshini R
Dr.Janet Jomon
Dr.Muhsin Muhammed A
Lijo Joseph Thomas

Abstract

Aim: The aim of the study is to evaluate prevalence of uropathogen and antibiotic susceptibility pattern in urinary tract infection in a tertiary care hospital.Method: This is a retrospective cohort study conducted over a period of 6 months in general medicine department of tertiary care hospital, Kerala. A total of 170 patients satisfying the inclusion criteria were analyzed. Case records were retrospectively reviewed for demographic data, clinical presentations, investigations, management and outcome. Data analysis were conducted using SPSS and Microsoft Excel 2010.Results: The majority of the patients causing urinary infection were females (61.2%) when compared with men (38.8%). Out of 170 patients, the age group >70 years were more prone to urinary tract infection. Of the total study group, Gram negative bacteria (97.1%) was the most prevalent organism causing urinary tract infection, among which E. coli (64.7%) predominates. E coli shows high sensitivity to amikacin. The most common antibiotic prescribed was found to be cefaperazone/sulbactam (30.6%).Conclusion: According to the study, urinary tract infections are highly prevalent in female patients >70 years of age. Regular surveillance and monitoring are extremely important to give practitioners the most recent information on the most efficient empirical treatment for urinary tract infections because antibiotic resistance among bacterial pathogens is evolving over time and space. Based on knowledge of the pattern of antibiotic susceptibility, empirical antibiotic selection should be made in the treatment of urinary tract infections.

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How to Cite
R, D., Jomon, D., Muhammed A, D. ., & Thomas, L. J. (2022). Prevalence of Uropathogen and Antibiotic Susceptibility Pattern in Urinary Tract Infection: A Reterospective Observational Cohort Study. International Journal of Medical Science and Clinical Research Studies, 2(9), 941–951. https://doi.org/10.47191/ijmscrs/v2-i9-07
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References

I. Convay H, Cnaan A, Zaoutis T et al. recurrent Urinary Tract Infection in Children Risk factors and Association with prophylactic antimicrobials. The Journal Of The American Association. 2007;298(2):179-186

II. Adukauskiene D, Cicinskaite I, Macas A et al. Hospital Aquired Urinary Tract infections. Uro PubMed centeral. 2016;42(12):957-964.

III. Odoki M, Aliero AA, Tibyangye J etal. Prevalance Of Bacterial Urinary Tract Infections And Associated Factors Among Patients Attending Hospitals in Bushenyi District, Uganda. International Journal Of Microbiology. 2019:1-8.

IV. Olowe OA, Makanjuola OB, Mabayoje VO et al. Detection of Bacteriuria Among Human Immuno Deficiency Virus Seropositive Individuals in Osogbo south western Nigeria. European Journal Of Microbiology and Immunology. 2015;5(1):126-130.

V. Foxman B. The Epidemiology Of Urinary Tract Infection: Economic considerations. Nature Reviews urology. 2010; 7:653-660.

VI. John AS, Mvoto CI and Agbo B. A review On The Prevalance And Predisposing factors responsible for Urinary Tract Infection among Adults. European Journal Of Experimental Biology. 2016;6(4): 7-11.

VII. Pardeshi P. Prevalence of Urinary Tract Infections and Current Scenario of Antibiotic Susceptibility Pattern of Bacteria Causing UTI. Indian Journal of Microbiology Research. 2018; 5(3): 334 – 338.

VIII. Seifu W D, and Gebissa A D. Prevalence and Antibiotic Susceptibility of Uropathogens from Cases of Urinary Tract Infections in Shashemene Referral Hospital, Ethiopia. BMC Infectious Diseases.2018; 18: 30.

IX. Chandrasekhar D, Dollychan A, Roy B M, Cholamughath S, and Parambil J C. Prevalence and antibiotic utilization pattern of uropathogens causing community-acquired urinary tract infection in Kerala, India. Journal of Basic Clinical Physiology and Pharmacology. 2018; 29(6): 671–677.

X. Dimitrov T S, Udo E E, Emara M, Awni F and Passadilla R. Etiology and Antibiotic Susceptibility Patterns of Community- Acquired Urinary Tract Infections in a Kuwait Hospital. Medical Principles and Practice.2004; 13: 334 – 339.

XI. Daoud N, Hamdoun M, Hannachi H et al. Antimicrobial Susceptibility Patterns of Escherichia coli among Tunisian Outpatients with Community-Acquired UTI. Current Urology. 2020; 14:200 – 205.

XII. Nguyen N V, Thuydo N T, Nguyen K T C et al. Community level consumption of antibiotics According to AWaRe classification in rural Vietnam. JAC-Antimicrobial Resistance.2020;3(2):1-8.

XIII. Alldredge B K, Corelli R L, Ernst M E, Guglielmo B J, Jacobson P A et al. Urinary tract infections. Koda - Kimble Young’s Applied Therapeutics: The clinical use of drugs, 10th edition.1594 – 1618.

XIV. Zeind C S and Carvalho M G. Urinary tract infections. Applied Therapeutics: The clinical use drugs, 11th edition. 2018; 3838 – 3894.

XV. Kabew G, Abebe T and Miheret A. A Retrospective study on prevalence and antimicrobial susceptibility patterns of bacterial isolates from UTI in Tikur Anbessa Specialized Teaching hospital Addis Ababa, Ethiopia. The Ethiopian Journal of Health Development. 2013; 27(2): 111- 117.

XVI. Folliero V, Caputo P, Rocca M T D, Chianese A, Galdiero M et al. Prevalence Antimicrobial , Susceptibility Patterns of Bacterial Pathogens in Urinary Tract Infections in University Hospital of Campania . Antibiotics 2020, 9, 215: 1-9.

XVII. Whittlesea C and Hodson K. Urinary tract infections. Clinical Pharmacy and Therapeutics, 6th edition. 2019; 623 – 634.

XVIII. Tomy A, Hareendran A, David E et al. Antimicrobial Susceptibility of Uropathogens and Prescribing Patterns in Hospital and Community-Acquired Urinary Tract Infections in a Tertiary Care Hospital. Journal of Applied Pharmaceutical Science. 2020; 10 (11): 50 – 58.

XIX. Prakash D and Saxena R S. Prevalence and Antimicrobial Susceptibility Pattern of Escherichia coli in Hospital Acquired and Community Acquired Patients Related to Urinary Tract Infection in India. Journal of Applied Pharmaceutical Science.2013; 3(8): 124 – 132.